Although it lacks its density of colonial monuments, slow-paced Carmelo, Uruguay, offers a glimpse of what Colonia del Sacramento was like before its tourism-driven gentrification. Located 235 km/145 km northwest of Montevideo, Carmelo has good boat connections to Argentina via the Buenos Aires suburb of Tigre, and it's an unpretentious destination with a few surprises—specifically, the restaurant at the nearby Four Seasons Resort Carmelo and the restaurant and wine bar at Finca Narbona, which is a winery as well as a working farm.

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